Zebrafish Tumors

Targeting zebrafish And Murine Pituitary Corticotroph tumors ...
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor Ning-Ai Liua, Hong Jiang3, Anat Ben-Shlomoa, Kolja Wawrowsky3, Xue-Mo Fanbr Shuo Lincr and Shlomo Melmed3,1 ... View Doc

Oncogenic KRAS Promotes Malignant Brain tumors In zebrafish
Activation of Ras and mTOR pathways in brain tumors In mouse models of oncogenic Kras-induced glioma, tumor cells have increased expression of both phosphory- ... Doc Viewer

Blood Vessels Sprout Under Pressure
It is blood pressure that drives the opening of small capillaries during angiogenesis. A team of researchers has observed the process for the first time. ... Read News

Zebrafish With Mutations In Mismatch Repair Genes Develop ...
Cancer Res€2008;68:5059-5066. € Harma Feitsma, Raoul V. Kuiper, Jeroen Korving, et al. € Neurofibromas and Other Tumors Zebrafish with Mutations in Mismatch Repair Genes Develop ... Read More

Diseases Of Zebrafish - CL Davis Fdn
Zebrafish Tumors • Studies of spontaneous and induced tumors in zebrafish show that they develop a wide variety of epithelial, mesenchymal, neuroepithelial, and neural crest neoplasms. • Zebrafish develop a number of histologic ... Access Document

Liver tumor Models In Transgenic zebrafish: An Alternative In ...
Special Report Tumors in the zebrafish Since the 1950s, and in particular in the past two decades, the zebrafish (Danio rerio) has been used as an excellent experimental model in developmental biology. In recent years, there ... Fetch Content

And Develop Neuroblastoma NIH Public Access 1, And Mol Cancer Res
Tumors with high penetrance that histologically resemble neuroblastoma. These tumors are clearly neural in origin, although they do not express catecholaminergic neuronal markers characteristic of human neuroblastoma. The zebrafish tumors result from inappropriate maintenance of a cell ... Document Retrieval

A Transgenic zebrafish Liver tumor Model With Inducible Myc ...
416 dmm.biologists.org RESEARCH ARTICLE Myc transgenic zebrafish as a liver tumor model transformed into tumor phenotype without the existence of normal liver tissue. ... Content Retrieval

Developing Drugs That Protect Against Radiation - YouTube
Thomas Jefferson University Hospitals doctors Adam Dicker, MD, PhD, professor and chairman of radiation oncology and Ulrich Rodeck, MD, PhD, a professor of dermatology, cutaneous biology and radiation oncology have used zebrafish for more than six years in an effort to identify ... View Video

Zebrafish As A Cancer Model - Molecular Cancer Research
Zebrafish as a Cancer Model Harma Feitsma and Edwin Cuppen Hubrecht Institute for Developmental Biology and Stem Cell Research, Utrecht, the Netherlands Abstract Zebrafish tumors resemble various types of human tumors at the histologic level. ... Fetch Doc

Comparative Oncogenomic Analysis Of Copy Number Alterations ...
Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery Citation Zhang, GuangJun, Sebastian Hoersch, Adam Amsterdam, ... Retrieve Full Source

Making Waves In Cancer Research: New Models In The zebrafish
The zebrafish (Danio rerio) is a small tropical fish that has become a powerful animal model system for understanding the genetic basis of zebrafish tumors can vary with the specific mutagen, indicating nonrandom activity. For example, the ... Fetch Here

Hypoxia-induced Pathological Angiogenesis Mediates tumor Cell ...
Our zebrafish tumor model, primary tumors remain in situ as tiny nodules and antiangiogenic drugs would not result in significant hypoxia as in a well-established tumor. Thus, tumor sizes might be a key determinant for antiangiogenic drug-produced therapeutic ... Document Viewer

Orthodenticle Homeobox 2 - Wikipedia, The Free Encyclopedia
Orthodenticle homeobox 2. Orthodenticle homeobox 2; PDB rendering based on 2dms. Available structures; PDB: Ortholog search: It has been shown that if Otx2 is over expressed it can lead to childhood malignant brain tumors called medulloblastomas. ... Read Article

Study Of Cancer’s Origins Reveals Genetic Reprogramming Of Single Cells
Researchers have created a model of cancer in zebrafish that allows them to capture live images of tumors forming and growing, in some cases from a single cell. ... Read News

ZebRAfish— In Cancer Research
While the animal is still alive, and it takes much less time and effort to gather the same data. Monitoring tumors and cancer progres-sion, however, is not the only thing that ... Return Document

RESEARCH ARTICLE Molecular And Cellular Characterization Of A ...
RESEARCH ARTICLE Molecular and Cellular Characterization of a Zebrafish Optic Pathway Tumor Line Implicates Glia-Derived Progenitors in Tumorigenesis ... Read Document

Transplantable Tumor Lines Generated In Clonal Zebrafish
Transplantable Tumor Lines Generated in Clonal Zebrafish Igor V. Mizgireuv1 and Sergei Y. Revskoy2,3 Transplantable zebrafish tumors are a novel and very promising model in cancer research. However, further prog- ... Get Content Here

Heterozygous Inactivation Of Tsc2 Enhances Tumorigenesis In ...
Title: “Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish” Running title: tumors in tsc2/p53 mutant animals By Seok-Hyung Kim, Marie L. Kowalski, Robert P. Carson, L. Richard Bridges, and Kevin C. Ess* ... Fetch Doc

Discriminating Different Cancer Cells Using A Zebrafish
Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay Karni S. Moshal, Karine F. Ferri-Lagneau, Jamil Haider, Pooja Pardhanani striking similarities in the molecular and histopathological features of zebrafish and human tumors ... Retrieve Document

Tp53mutant zebrafish Develop Malignant Peripheral Nerve ...
Tp53mutant zebrafish develop malignant peripheral nerve sheath tumors Ste´phane Berghmans*†, Ryan D. Murphey†‡, Erno Wienholds§, Donna Neuberg¶, Jeffery L. Kutok , ... Access Doc

Watch this medical education video about the structure and function of pericytes and improve your histology knowledge! Using Zebrafish to Study and Model Cancer - Duration: Malignant Bone Forming Tumors (Osteosarcoma) - Lecture 4 - Duration: 59:59. James C. Wittig, ... View Video

Loss Of P53 Synthesis In zebrafish Tumors With Ribosomal ...
Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations Alyson W. MacInnes, Adam Amsterdam, Charles A. Whittaker, Nancy Hopkins*, and Jacqueline A. Lees* ... Doc Viewer